子痫前期患者的全血粘度

Whole blood viscosity in preeclampsia.

作者信息

Hobbs J B, Oats J N, Palmer A A, Long P A, Mitchell G M, Lou M, McIver M A

出版信息

Am J Obstet Gynecol. 1982 Feb 1;142(3):288-92. doi: 10.1016/0002-9378(82)90732-3.

Abstract

Whole blood viscosity was measured in 41 patients with preeclampsia and in 51 normotensive control subjects. The mean viscosity in the preeclamptic group had a highly significant elevation (t = 9.752, p less than 0.001, at a shear rate of 0.1 sec-1 and t = 4.223, p less than 0.001, at a shear rate of 100 sec-1). The slower shear rate gave the better discrimination between the two groups as only four patients with preeclampsia had a value within 1 SD of the mean of the control group. It is suggested that the measurement of whole blood viscosity may be clinically useful in the management of patients with preeclampsia.

摘要

对41例先兆子痫患者和51例血压正常的对照者进行了全血粘度测量。先兆子痫组的平均粘度有高度显著升高（在剪切速率为0.1秒-1时，t = 9.752，p < 0.001；在剪切速率为100秒-1时，t = 4.223，p < 0.001）。较慢的剪切速率能更好地区分两组，因为只有4例先兆子痫患者的值在对照组平均值的1个标准差范围内。有人提出，全血粘度测量在先兆子痫患者的管理中可能具有临床应用价值。