Krebs H B, Petres R E, Dunn L J, Smith P J
Am J Obstet Gynecol. 1982 Feb 1;142(3):297-305. doi: 10.1016/0002-9378(82)90734-7.
The fetal heart rate (FHR) tracings of 1,996 fetuses were analyzed to assess the prognostic value of accelerations in early labor and just prior to delivery. Accelerations were divided into periodic and sporadic types according to their association or lack of association with uterine contractions. It is shown that two or less sporadic accelerations per 30 minutes are unfavorable. Three accelerations indicate fetal well-being as much as any higher number of accelerations per 30 minutes. FHR abnormalities coexistent with three or more sporadic accelerations were found to have a better prognosis than FHR abnormalities associated with two or less sporadic accelerations. Fetuses exhibiting low FHR variability commonly showed lack of accelerations, whereas normal FHR variability was almost invariably accompanied by sporadic accelerations. The pathogenesis of accelerations is discussed. It is concluded that accelerations are indicators of fetal well-being, whereas the lack of accelerations with lack of reactivity to manipulation of the fetus may be indicative of severe fetal hypoxia with fetal acidemia. This conclusion is supported by fetal outcome and determination of pH from fetal scalp blood.
对1996例胎儿的胎心率(FHR)描记图进行分析,以评估产程早期及临产前加速的预后价值。根据加速与子宫收缩的关联与否,将加速分为周期性和散发性两种类型。结果显示,每30分钟散发性加速少于两次提示预后不良。三次加速提示胎儿状况良好,与每30分钟更多次数的加速提示效果相同。发现与三次或更多散发性加速并存的FHR异常,其预后优于与两次或更少散发性加速相关的FHR异常。FHR变异低的胎儿通常显示无加速,而正常FHR变异几乎总是伴有散发性加速。文中讨论了加速的发病机制。得出的结论是,加速是胎儿状况良好的指标,而无加速且对胎儿操作无反应可能提示严重胎儿缺氧伴胎儿酸血症。这一结论得到了胎儿结局及胎儿头皮血pH测定结果的支持。