Hull S, Mathews J A
Ann Rheum Dis. 1982 Feb;41(1):21-4. doi: 10.1136/ard.41.1.21.
In rheumatoid disease only 4 cases have been reported in which lung nodules preceded arthritis. Two further cases are presented in which intrapulmonary nodules were noted at the onset of the disease, thus provoking a diagnostic dilemma. In the first patient rheumatoid factor tests were initially negative, and diagnostic thoracotomy was performed. In the second patient serological tests were positive, and biopsy was avoided. It therefore seems that detection of circulating rheumatoid factor in patients with lung shadows can be a useful aid to diagnosis and management.
在类风湿病中，仅有4例报告显示肺部结节先于关节炎出现。本文还介绍了另外2例，这2例患者在疾病发作时发现了肺内结节，从而引发了诊断难题。第一例患者类风湿因子检测最初为阴性，随后进行了诊断性开胸手术。第二例患者血清学检测呈阳性，因此未进行活检。由此可见，对有肺部阴影的患者检测循环类风湿因子，可能有助于诊断和治疗。
