Morley J E, Shafer R B
Arch Intern Med. 1982 Mar;142(3):591-3.
Thyroid function screening may be of value in psychiatric patients. The present study was undertaken to determine the incidence of thyroid abnormalities in psychiatric patients during short-term admissions. Results of thyroid function tests disclosed an elevated free thyroxine index (FT4I) and free triiodothyronine index (FT3I) in 19% of 386 psychiatric patients during short-term admissions to Minneapolis Veterans Administration Medical Center. Elevated test results were particularly common in paranoid schizophrenics (38%) and in patients with amphetamine abuse (32%). On retesting, at two to three weeks after hospitalization, the FT4I and FT3I had returned to normal in 13 of 16 and 17 of 17 patients, respectively. Undiagnosed hypothyroidism was found in four patients with a diagnosis of manic-depressive psychosis on hospital admission. Serial sampling needs to be undertaken to assess the most appropriate time for thyroid function testing after short-term psychiatric admission.
甲状腺功能筛查对精神科患者可能有价值。本研究旨在确定短期住院精神科患者甲状腺异常的发生率。甲状腺功能测试结果显示，在明尼阿波利斯退伍军人管理局医疗中心短期住院的386名精神科患者中，19%的患者游离甲状腺素指数（FT4I）和游离三碘甲状腺原氨酸指数（FT3I）升高。检测结果升高在偏执型精神分裂症患者（38%）和苯丙胺滥用患者（32%）中尤为常见。在住院两到三周后重新检测时，16名患者中的13名以及17名患者中的17名的FT4I和FT3I分别恢复正常。入院时诊断为躁狂抑郁症的4名患者中发现了未确诊的甲状腺功能减退。需要进行系列采样，以评估短期精神科入院后进行甲状腺功能测试的最合适时间。
