Mortimer D, Richardson D W
Br J Obstet Gynaecol. 1982 Feb;89(2):132-5. doi: 10.1111/j.1471-0528.1982.tb04679.x.
A survey of available data has shown that the sex ratio of births is significantly affected both by the practice of artificial insemination (AI) and by the cryostorage of semen. Comparison of the sex ratio of all infants born in England, Scotland and Wales between 1969 and 1978 (51.5% males) with that of British births after AI showed that the prevalence rate of male births after AI with either fresh or cryostored semen was lower than that for the general population: fresh semen (47.8%); cryostored semen (42.9%). When data from European countries and the US were combined, AI with fresh semen significantly increased the prevalence rate of male infants to 57.7%, whereas AI with cryostored semen significantly decreased the rate to 49.7%. The mechanism/s whereby the cryostorage of spermatozoa affects the secondary sex ratio remains to be determined.
一项对现有数据的调查表明，出生性别比受到人工授精（AI）操作和精液冷冻保存的显著影响。将1969年至1978年间在英格兰、苏格兰和威尔士出生的所有婴儿的性别比（男性占51.5%）与人工授精后英国出生婴儿的性别比进行比较，结果显示，使用新鲜或冷冻精液进行人工授精后出生的男婴患病率低于普通人群：新鲜精液（47.8%）；冷冻精液（42.9%）。当欧洲国家和美国的数据合并后，使用新鲜精液进行人工授精显著提高了男婴患病率至57.7%，而使用冷冻精液进行人工授精则显著降低至49.7%。精子冷冻保存影响第二性别比的机制仍有待确定。
