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Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution.

作者信息

Patel D J, Kozlowski S A, Marky L A, Rice J A, Broka C, Dallas J, Itakura K, Breslauer K J

出版信息

Biochemistry. 1982 Feb 2;21(3):437-44. doi: 10.1021/bi00532a003.

DOI:10.1021/bi00532a003
PMID:7066295
Abstract
摘要

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Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution.溶液中自互补双链体d(CGTGAATTCGCG) 中脱氧鸟苷-胸苷摆动碱基对形成的结构、动力学和能量学
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2
Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution.在溶液中,额外的腺苷堆积到自身互补的d(CGCAGAATTCGCG)双链体中。
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Theoretical study of the geometrical arrangement of GT and GA wobble pairs in two short duplexes, Proton NMR chemical shifts and interaction energy calculations.
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Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove.DNA双链中与 -2 缺失位点相对的 [AF]dG 的溶液构象:共价连接的氨基芴环嵌入螺旋,同时 C8 修饰的顺式鸟嘌呤和相邻未配对的 3'-腺嘌呤碱基位移至大沟中。
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Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.DNA双链中与dC相对的(-)-顺式-反式苯并[a]芘基-dG加合物的溶液构象:共价连接的BP环插入螺旋,修饰的脱氧鸟苷碱基位移至大沟。
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Wobble dG X dT pairing in right-handed DNA: solution conformation of the d(C-G-T-G-A-A-T-T-C-G-C-G) duplex deduced from distance geometry analysis of nuclear Overhauser effect spectra.右手螺旋DNA中的摆动dG·X·dT碱基对:通过核Overhauser效应光谱的距离几何分析推导的d(C-G-T-G-A-A-T-T-C-G-C-G)双链体的溶液构象
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