Aα链在钙与人类纤维蛋白原结合中的潜在作用。
Potential role of the A alpha chain in the binding of calcium to human fibrinogen.
作者信息
Marguerie G, Ardaillou N
出版信息
Biochim Biophys Acta. 1982 Mar 4;701(3):410-2. doi: 10.1016/0167-4838(82)90246-1.
PMID:7066337
Abstract
The binding of Ca2+ to human fibrinogen was investigated. Molecules with intact A alpha chain possessed three high-affinity binding sites but fibrinogen samples with partially degraded A alpha chain exhibited only two sites. It is therefore suggested that the integrity of this chain is required for the interaction between the protein and this cation.
摘要
研究了钙离子与人纤维蛋白原的结合情况。具有完整Aα链的分子拥有三个高亲和力结合位点，但Aα链部分降解的纤维蛋白原样品仅显示出两个位点。因此，表明该链的完整性是蛋白质与该阳离子之间相互作用所必需的。
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