Plotka E D, Seal U S, Verme L J, Ozoga J J
Biol Reprod. 1982 Mar;26(2):258-62. doi: 10.1095/biolreprod26.2.258.
The primary source of progesterone during pregnancy in white-tailed deer (Odocoileus virginianus borealis) was examined in two experiments. Ovariectomy at 110 or 156 days of gestation reduced progesterone levels in jugular vein blood serum from 5.1 +/- 0.7 ng/ml to 0.3 +/- 0.1 ng/ml and resulted in termination of pregnancy. Sham-operated does maintained pregnancy and preoperative progesterone levels. Measured at 110 days gestation in three does, progesterone concentrations in ovarian vein, uterine artery and vein, and jugular vein blood serum averaged 319.3 +/- 29.3, 5.9 +/- 0.3, 46.7 +/- 8.9, and 4.9 +/- 0.4 ng/ml, respectively. Ovarian vein concentrations of progesterone fluctuated over a 2-3/4 h collection period between 70 and 1200 ng/ml. Uterine and jugular vein concentrations of progesterone fluctuated less dramatically. These experiments suggest that the ovaries are the principal source of progesterone through the first 156 days of the normal 200-day gestation in white-tailed deer and that the ovaries are essential for maintenance of pregnancy during this time.
在两项实验中研究了白尾鹿（弗吉尼亚鹿指名亚种，Odocoileus virginianus borealis）孕期孕酮的主要来源。在妊娠110天或156天时进行卵巢切除术，可使颈静脉血清中的孕酮水平从5.1±0.7 ng/ml降至0.3±0.1 ng/ml，并导致妊娠终止。接受假手术的母鹿维持妊娠及术前孕酮水平。在三只母鹿妊娠110天时测量发现，卵巢静脉、子宫动脉和静脉以及颈静脉血清中的孕酮浓度分别平均为319.3±29.3、5.9±0.3、46.7±8.9和4.9±0.4 ng/ml。在2至3/4小时的采集期内，卵巢静脉中的孕酮浓度在70至1200 ng/ml之间波动。子宫和颈静脉中的孕酮浓度波动较小。这些实验表明，在白尾鹿正常200天妊娠期的前156天，卵巢是孕酮的主要来源，且在此期间卵巢对于维持妊娠至关重要。
