Immunochemical and electrophoretic study of glycoproteins in cancer patients.

Glycoproteins have been studied in the past and found to be elevated in human malignancies, as well as degenerative, traumatic or inflammatory diseases. In order to obtain insight into the relationship of these plasma proteins to malignancy, we studied 78 patients with various neoplasms and compared the values of alpha 1-acid glycoprotein (orosomucoid), alpha 1 glycoprotein and carcinoembryonic antigen (CEA). Normal values were calculated for these parameters in sera of 100 normal individuals.