Denton J R
Clin Orthop Relat Res. 1982 Jan-Feb(162):91-8.
Ninety-four patients with congenital imperforate anus were studied to investigate: (1) the incidence of congenital spinal anomalies; (2) the orthopedic significance of these anomalies; (3) the incidence of other musculoskeletal disorders; and (4) the incidence of anomalies in other organ systems in the anal-spine anomaly group. There was a 38% incidence of spinal anomalies in 94 patients with congenital imperforate anus. Most of these abnormalities were sacral, and there were no related or progressive spinal deformities. The incidence of other musculoskeletal anomalies was much lower than of the spine (only 9% of the total). The triad of caudal regression-imperforate anus, spinal anomalies, and genitourinary tract anomalies-was present in 19 (53%) of the 36 cases, much more than any other combination of major system abnormalities such as the VATER of VACTEL syndromes.
对94例先天性肛门闭锁患者进行了研究，以调查：（1）先天性脊柱异常的发生率；（2）这些异常的骨科意义；（3）其他肌肉骨骼疾病的发生率；以及（4）肛门-脊柱异常组中其他器官系统异常的发生率。94例先天性肛门闭锁患者中脊柱异常的发生率为38%。这些异常大多为骶骨异常，且无相关或进行性脊柱畸形。其他肌肉骨骼异常的发生率远低于脊柱异常（仅占总数的9%）。在36例病例中有19例（53%）出现了尾骨退化-肛门闭锁、脊柱异常和泌尿生殖道异常三联征，比任何其他主要系统异常组合（如VATER或VACTEL综合征）都要多得多。
