Tyson H, Fields M A
Comput Programs Biomed. 1982 Feb;14(1):77-84. doi: 10.1016/0010-468x(82)90093-9.
The fitting of linear additive models to data by weighted least squares methods has been programmed in BASIC. By splitting up the matrix solution into several steps, the RAM memory space needed in a microprocessor by the corresponding programs was reduced, allowing room for larger matrices. Storage of intermediate products, and of subsequent programs in the sequence , was on a mini floppy dual-disc drive. Using an extended BASIC interpreter permitting several files to be open during a program, the program package compromised between computing time and problem size. Problems involving 1600 element matrices were run on a micro having 32000 bytes of memory, allowing for example, the fitting of a model with 22 parameters to 72 observations.
用加权最小二乘法将线性加法模型拟合到数据的过程已用BASIC语言编程实现。通过将矩阵求解过程分解为几个步骤，相应程序在微处理器中所需的随机存取存储器（RAM）空间得以减少，从而为更大的矩阵留出了空间。中间结果以及后续程序按顺序存储在一个小型双软盘驱动器上。使用一个允许在程序运行期间打开多个文件的扩展BASIC解释器，该程序包在计算时间和问题规模之间进行了权衡。涉及1600个元素矩阵的问题在一个具有32000字节内存的微型计算机上运行，例如，可以将一个具有22个参数的模型拟合到72个观测值上。
