Van Peteghem C, Heyndrickx A, Van Zele W
Eur J Drug Metab Pharmacokinet. 1982 Jan-Mar;7(1):1-3. doi: 10.1007/BF03189535.
By means of a highly specific and sensitive mass fragmentographic method mescaline was measured in rabbit plasma samples, taken at various points after an i.v. injection. The pharmacokinetic behaviour conformed to the two-compartment open model. Half-life times of alpha and beta phases, velocity constants and steady-state distribution volumes of four subjects are reported.
通过一种高度特异性和灵敏的质量碎片图谱法,对静脉注射后不同时间点采集的家兔血浆样本中的三甲氧苯乙胺进行了测定。药代动力学行为符合二室开放模型。报告了四名受试者的α相和β相半衰期、速度常数以及稳态分布容积。