Zellweger J P, Leuenberger P J
Eur J Respir Dis. 1982 Mar;63(2):94-101.
Transbronchial lung biopsy via the fiberoptic bronchoscope has been proposed for the diagnosis of diffuse lung diseases, particularly sarcoidosis. This study reports results in 167 patients. Lung parenchyma was obtained i 143 patients (85.6%). A cytologic or histologic picture compatible with the clinical presentation was found in 62.3% of all cases. Percentage of positive results was related to the study groups under consideration: 75.6% for diffuse interstitial infiltrates, 50.0% for chronic localized infiltrates, 52.0% fro solitary nodules, 73.5% for sarcoidosis (69.8% at stages 0 and I, 83.0% at stage II, 75.0% at stage III); and 54.4% for infectious pneumonitis. Complications included pneumothorax and bronchial hemorrhage, but were rare (4%) and minor. Because of its low morbidity and high diagnostic yield, fiberoptic transbronchial lung biopsy is the diagnostic tool of choice in various respiratory diseases, whether diffuse or localized.
经纤维支气管镜进行经支气管肺活检已被用于诊断弥漫性肺部疾病，尤其是结节病。本研究报告了167例患者的结果。143例患者（85.6%）获取了肺实质。在所有病例中，62.3%发现了与临床表现相符的细胞学或组织学表现。阳性结果的百分比与所考虑的研究组相关：弥漫性间质浸润为75.6%，慢性局限性浸润为50.0%，孤立性结节为52.0%，结节病为73.5%（0期和I期为69.8%，II期为83.0%，III期为75.0%）；感染性肺炎为54.4%。并发症包括气胸和支气管出血，但很少见（4%）且较轻微。由于其低发病率和高诊断率，纤维支气管镜经支气管肺活检是各种呼吸系统疾病（无论是弥漫性还是局限性）的首选诊断工具。
