Tomlinson M J, Perman V, Westlake R L
J Am Vet Med Assoc. 1982 Mar 15;180(6):622-6.
Urate nephrolithiasis with epistaxis and bleeding around foot pads was diagnosed in ranch mink. Investigation of affected, unaffected-related, and unaffected-unrelated mink did not disclose the cause of these problems but did eliminate inherited bleeding disorders as a cause of the bleeding. All affected mink were males, had been sired by related sires, and were affected in the 1st year of life. Elimination of affected mink and their parents from the breeding stock eliminated the condition from the herd. The findings were consistent with an inherited defect in uric acid metabolism or excretion.
在牧场水貂中诊断出患有尿酸肾结石、鼻出血和脚垫周围出血的病症。对患病、患病相关和未患病无关的水貂进行调查,未发现这些问题的病因,但排除了遗传性出血性疾病是出血原因的可能性。所有患病水貂均为雄性,由相关种公貂所生,且在出生第一年就出现病症。从种畜群中剔除患病水貂及其父母后,该病症在畜群中消失。这些发现与尿酸代谢或排泄的遗传性缺陷相符。