Nishida E, Sakai H
J Biochem. 1982 Jan;91(1):411-4. doi: 10.1093/oxfordjournals.jbchem.a133703.
An actin-regulatory protein, 88 K protein-actin complex (88 K-actin complex) isolated from porcine brain, increases the rate of actin polymerization as measured by viscometry which gives rise to shearing stresses. In contrast, when measured by the optical absorption method without solvent flow, the complex does not promote actin polymerization but inhibits both the initial rate and final extent of polymerization. These results suggest that shearing stresses are capable of modulating association of actin with the 88 K-actin complex.
一种从猪脑中分离出的肌动蛋白调节蛋白，即88K蛋白-肌动蛋白复合物（88K-肌动蛋白复合物），通过粘度测定法测量发现其能增加肌动蛋白聚合速率，而粘度测定会产生剪切应力。相比之下，当采用无溶剂流动的光吸收法测量时，该复合物不会促进肌动蛋白聚合，反而会抑制聚合的初始速率和最终程度。这些结果表明，剪切应力能够调节肌动蛋白与88K-肌动蛋白复合物的结合。
