营养变异轻型链球菌对维生素B6的需求
Vitamin B6 requirements of nutritionally variant Streptococcus mitior.
作者信息
Schiller N L, Roberts R B
出版信息
J Clin Microbiol. 1982 Apr;15(4):740-3. doi: 10.1128/jcm.15.4.740-743.1982.
Abstract
The growth rate of three vitamin B6-dependent Streptococcus mitior (B6DS) and two non-B6DS strains in Todd-Hewitt broth, with and without vitamin B6 supplementation, was examined. Even in optimally supplemented culture media, the growth rate of the three B6DS strains was much slower than that of comparable non-B6DS strains. Uptake studies with [3H] pyridoxine suggest that these B6DS strains cannot assimilate pyridoxine. Although not transported intracellularly, pyridoxine inhibited the growth of B6DS strains in media supplemented with other vitamin B6 analogs, probably by binding to the vitamin B6 transport system and inhibiting the uptake of the other vitamin B6 analogs.
摘要
研究了三株维生素B6依赖型缓症链球菌（B6DS）和两株非B6DS菌株在添加和不添加维生素B6的托德-休伊特肉汤中的生长速率。即使在添加了最佳量维生素的培养基中，三株B6DS菌株的生长速率也比可比的非B6DS菌株慢得多。用[3H]吡哆醇进行的摄取研究表明，这些B6DS菌株不能同化吡哆醇。尽管吡哆醇不能转运到细胞内，但它在添加了其他维生素B6类似物的培养基中抑制了B6DS菌株的生长，可能是通过与维生素B6转运系统结合并抑制其他维生素B6类似物的摄取。
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Nature. 1961 Aug 12;191:728-30. doi: 10.1038/191728a0.
2
Evaluation of blood culture media for isolation of pyridoxal-dependent Streptococcus mitior (mitis).用于分离吡哆醛依赖性缓症链球菌（轻链球菌）的血培养基评估。
J Clin Microbiol. 1981 Sep;14(3):266-72. doi: 10.1128/jcm.14.3.266-272.1981.
3
Bacterial persistence in streptococcal endocarditis due to thiol-requiring mutants.由需硫醇突变体导致的链球菌性心内膜炎中的细菌持续存在。
J Infect Dis. 1971 Sep;124(3):247-54. doi: 10.1093/infdis/124.3.247.
4
Bacteremia and endocarditis caused by satelliting streptococci.卫星状链球菌引起的菌血症和心内膜炎。
Am J Clin Pathol. 1974 May;61(5):585-91. doi: 10.1093/ajcp/61.5.585.
5
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