Suzuki S
Nihon Sanka Fujinka Gakkai Zasshi. 1982 Apr;34(4):538-40.
From the viewpoint of fetal distress related disseminated intravascular coagulation (DIC), the Hageman Factor, kinin-kallikrein system were investigated and on the other hand the adaptation of the normal newborn to extrauterine life was also evaluated. (1) The Kininogen volume of the cord venous blood was approximately 1/2-1/3 or there abouts and was remarkable in serious cases of asphyxiated newborn. (2) In a similar manner the Hageman factor decreases in asphyxiated newborn. On the other hand, SFMC increases in aspyxiation as well as FDP. According to these results, there seems to be a coagulation obstruction due to consumption. Or it may be interpreted as an inhibition of kinin separation. In any event it may be considered as a rational contribution to the living body. (3) Based on the above, in cases of serious asphyxiation, DIC may possibly play a role and in these cases and the kininkallikrein system may be one of the mediators.
从胎儿窘迫相关弥散性血管内凝血（DIC）的角度，对激肽释放酶原系统和激肽 - 缓激肽系统进行了研究，另一方面，也评估了正常新生儿对宫外生活的适应性。（1）脐带静脉血中激肽原含量约为正常的1/2 - 1/3左右，在重度窒息新生儿病例中尤为显著。（2）同样，窒息新生儿体内的凝血因子Ⅻ减少。另一方面，纤维蛋白单体稳定复合物（SFMC）以及纤维蛋白降解产物（FDP）在窒息时增加。根据这些结果，似乎存在因消耗导致的凝血障碍。或者可以解释为激肽释放受到抑制。无论如何，这可能被认为是对机体的一种合理作用。（3）基于上述情况，在重度窒息病例中，DIC可能发挥作用，在这些病例中，激肽 - 缓激肽系统可能是介导因素之一。
