杜兴氏肌营养不良症中淋巴细胞帽化的评估。

An evaluation of lymphocyte capping in Duchenne muscular dystrophy.

作者信息

Nicholson G A, Sugars J

出版信息

J Neurol Sci. 1982 Mar;53(3):511-8. doi: 10.1016/0022-510x(82)90247-7.

Abstract

There have been conflicting reports of lymphocyte capping abnormalities in Duchenne muscular dystrophy (DMD). We have evaluated the original method described by Verrill et al. in a "blind" study of 24 Duchenne muscular dystrophy boys and paired age-matched control boys. We found no differences in capping between the two groups but control boys had decreased capping compared to a group of normal adult males and females. It is concluded that the initial reports of decreased capping in DMD may have been due to differences in age between the test and control group.

摘要

关于杜氏肌营养不良症（DMD）患者淋巴细胞帽化异常的报道存在矛盾。我们在一项针对24名杜氏肌营养不良症男孩及与之年龄匹配的对照男孩的“盲法”研究中，对Verrill等人描述的原始方法进行了评估。我们发现两组之间的帽化没有差异，但与一组正常成年男性和女性相比，对照男孩的帽化有所降低。得出的结论是，最初关于DMD患者帽化降低的报道可能是由于测试组和对照组之间的年龄差异。