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晚期癌肿的支气管成形肺叶切除术:功能变化与生存率

Bronchoplastic lobectomies for advanced carcinoma: functional changes and survival.

作者信息

Vanderhoeft P

出版信息

Acta Chir Belg. 1978 Jul-Aug;77(4):293-302.

PMID:706966
Abstract

Twenty-five patients underwent "sleeve" or "wedge" lobectomies for bronchogenic carcinoma: 24 squamous cell type and one adenocarcinoma. In 6, the tumor extended to a segmental bronchus (T1) in 15 to a lobar bronchus (T2) and in 4 to a main brochus (T3): 19 were in the right lung, 6 in the left. Eight patients had no lymph node involvement (N0), 10 tumors had spread to hilar nodes (N1), and 7 to mediastinal nodes (N2). There were 11 "sleeve" and 14 "wedge" bronchoplasties. Two patients developed a bronchopleural fistula: one of them died 2 weeks after pneumonectomy, the only death related to the procedure. A third patient had a local recurrence. Plethysmography, bronchospirography and Xe133 gammagraphy were performed in six patients. Lung volumes usually decreased but dynamics were unchanged or even improved after "sleeve" resection. After "wedge" resection all parameters were impaired. Twelve patients have died of cancer after a mean survival time of 16 months. Four of the 10 eligible patients have survived 5 years and more; seven patients are alive less than 5 years.

摘要

25例患者因支气管源性癌接受了“袖状”或“楔形”肺叶切除术:24例为鳞状细胞型,1例为腺癌。6例肿瘤侵犯至段支气管(T1),15例侵犯至叶支气管(T2),4例侵犯至主支气管(T3):19例位于右肺,6例位于左肺。8例患者无淋巴结转移(N0),10例肿瘤已扩散至肺门淋巴结(N1),7例扩散至纵隔淋巴结(N2)。共进行了11例“袖状”和14例“楔形”支气管成形术。2例患者发生支气管胸膜瘘:其中1例在肺切除术后2周死亡,这是与手术相关的唯一死亡病例。第3例患者出现局部复发。对6例患者进行了体积描记法、支气管呼吸描记法和Xe133闪烁照相术。“袖状”切除术后肺容积通常减小,但动态功能无变化甚至有所改善。“楔形”切除术后所有参数均受损。12例患者在平均生存16个月后死于癌症。10例符合条件的患者中有4例存活了5年及以上;7例患者存活时间不到5年。

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