Thomas M, Chilvers A S, Hall P T
J R Soc Med. 1982 Apr;75(4):228-30. doi: 10.1177/014107688207500403.
Over a two-year period 30 patients in a British district general hospital had human umbilical vein grafts (Meadox Medical) inserted for severe lower limb ischaemia. There were no perioperative deaths but 6 patients subsequently died from their atherosclerosis. The cumulative patency rate at one year was 70%. Five patients suffered immediate graft failure and all required amputation. Failures were due to inappropriate case selection and early technical inexperience with handling the graft.
在两年时间里,英国一家地区综合医院的30名患者因严重下肢缺血接受了人脐静脉移植物(Meadox Medical公司产品)植入手术。围手术期无死亡病例,但随后有6名患者死于动脉粥样硬化。一年时的累积通畅率为70%。5名患者出现移植物立即失效,均需截肢。失败原因是病例选择不当以及早期处理移植物的技术经验不足。