Narayan P, Lange P H, Fraley E E
J Urol. 1982 Apr;127(4):685-8. doi: 10.1016/s0022-5347(17)53996-8.
We studied ejaculation and fertility in 55 men who had undergone suprahilar extended retroperitoneal lymphadenectomy for nonseminomatous testicular cancer between 1972 and 1980. Antegrade ejaculation had returned spontaneously in 25 patients, with sperm counts of 35 to 190 million per ml., and normal morphology and motility in 20. The other 5 men either refused to provide semen for analysis or had had vasectomies but all had fathered children postoperatively. Ten men in whom antegrade ejaculation had not returned spontaneously were treated wih sympathomimetic drugs. Antegrade ejaculation was induced in 5 patients, 1 of whom fathered a child while taking the drugs. Two other patients who had only small volumes of ejaculate also responded well to sympathomimetic drugs. A therapeutically sound retroperitoneal node dissection can be performed for testicular cancer without impairing fertility permanently in a significant number of patients.
我们研究了1972年至1980年间因非精原细胞瘤性睾丸癌接受肾门上极扩大腹膜后淋巴结清扫术的55名男性的射精和生育情况。25例患者顺行射精已自然恢复，精子计数为每毫升3500万至1.9亿，其中20例形态和活力正常。另外5名男性要么拒绝提供精液进行分析，要么已接受输精管切除术，但他们术后均育有子女。10例顺行射精未自然恢复的男性接受了拟交感神经药物治疗。5例患者诱导出顺行射精，其中1例在服药期间育有子女。另外2例射精量少的患者对拟交感神经药物也有良好反应。对于睾丸癌，可以进行治疗效果良好的腹膜后淋巴结清扫术，而不会在大量患者中永久性损害生育能力。
