[Clinicophysiological changes in the human body during prolonged head-down tilt hypokinesia].

By clinical-physiological and biochemical methods adaptation to prolonged (182 days) head-down tilting (--4.5 degrees) was investigated. It was found that man exposed to hypokinesia for a month or longer, with countermeasures lacking, showed polymorphic clinical-physiological and biochemical disorders accompanied by a decline of his adaptive capabilities. This may aggravate further adaptation and readaptation processes.