Shimko I A
Kosm Biol Aviakosm Med. 1982 Mar-Apr;16(2):64-70.
Young rats, beginning with the age of 1 month, were kept in small size cages for 3 months, i.e., were exposed to 3-month motor deprivation. This exposure caused a modulating effect of a diminished activity of neuronal populations in the sensorimotor cortex which manifested as a prolongation of the latent periods of primary responses and recovery cycles of excitation of the neuronal populations generating the responses. The differences in the opposite changes in the sensorimotor cortex of the young animals that developed following prolonged deprivation and training of similar duration were seen in the parameters of excitation recovery cycles rather than in the latent periods. The reserve capabilities of the developing cortical structure associated with the modulation of excitation recovery cycles during training were 2.0-2.5 times greater than the dysfunctional changes in the same neuronal populations during motor deprivation. Both early motor deprivation and training did not influence the heterochronic development, emergence and subsequent attainment of the maximum amplitude of components of the testing primary response in the process of a gradual increase of the stimulus-to-stimulus interval.
从1月龄开始，将幼鼠饲养在小笼子里3个月，即使其经历3个月的运动剥夺。这种暴露导致感觉运动皮层中神经元群体活动减弱的调节作用，表现为产生反应的神经元群体的初级反应潜伏期和兴奋恢复周期延长。在长时间剥夺和类似持续时间训练后，幼小动物感觉运动皮层中相反变化的差异，在兴奋恢复周期参数而非潜伏期参数中可见。与训练期间兴奋恢复周期调节相关的发育中皮层结构的储备能力，比运动剥夺期间相同神经元群体的功能失调变化大2.0 - 2.5倍。早期运动剥夺和训练均未影响在刺激间隔逐渐增加过程中测试初级反应成分的异时发育、出现及随后达到的最大振幅。
