Kalisman M, Goldberg R, Ship A G
Plast Reconstr Surg. 1982 Apr;69(4):694-6. doi: 10.1097/00006534-198204000-00023.
A very unusual hand malformation is reported in which dorsal skin and nails exist on the volar aspect of the hands. This patient also exhibits mental retardation and microcephaly as well as a partial deletion of chromosome 6. Fifty percent of a small series of patients previously reviewed who presented with chromosome 6 abnormalities demonstrated abnormalities of the hands. Unusual deformities of the hands associated with mental retardation and microcephaly may be related to an abnormality of chromosome 6.
据报道，有一例非常罕见的手部畸形，其手掌掌面存在背部皮肤和指甲。该患者还表现出智力发育迟缓、小头畸形以及6号染色体部分缺失。在之前回顾的一小批患有6号染色体异常的患者中，50%表现出手部异常。与智力发育迟缓和小头畸形相关的手部异常畸形可能与6号染色体异常有关。
