Horne M K, Cooper B
South Med J. 1982 Apr;75(4):503-4. doi: 10.1097/00007611-198204000-00040.
Microangiopathic hemolytic anemia developed in two patients with metastatic malignancy, one with primary carcinoma of the colon and the other with ovarian carcinoma. There was no evidence of consumptive coagulopathy except severe thrombocytolysis in one patient. Both patients improved remarkably after chemotherapy. The colonic carcinoma responded to 5-fluorouracil delivered into the hepatic artery, and the ovarian tumor to multiagent systemic therapy.
两名转移性恶性肿瘤患者发生了微血管病性溶血性贫血，其中一名患有结肠癌，另一名患有卵巢癌。除一名患者出现严重血小板溶解外，没有消耗性凝血病的证据。两名患者在化疗后均有显著改善。结肠癌对经肝动脉注入的5-氟尿嘧啶有反应，卵巢肿瘤对多药全身治疗有反应。
