抗-Cob引起急性溶血性输血反应。

Anti-Cob causing acute hemolytic transfusion reaction.

作者信息

Lee E L, Bennett C

出版信息

Transfusion. 1982 Mar-Apr;22(2):159-60. doi: 10.1046/j.1537-2995.1982.22282177127.x.

DOI:10.1046/j.1537-2995.1982.22282177127.x

PMID:7071920

Abstract

An example of anti-Cob which caused an acute hemolytic transfusion reaction is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that weakly bound complement and reacted in the antiglobulin phase of the crossmatch. The unit of whole blood implicated in the hemolytic transfusion reaction was from a donor who was phenotyped as Co(a+b+). The patient gave no history of previous transfusions; however, anti-E and anti-c were also present.

摘要

报道了1例由抗-Cob引起急性溶血性输血反应的病例。免疫血液学研究表明，该抗体为IgG免疫球蛋白，与补体结合较弱，在交叉配血的抗球蛋白试验阶段发生反应。与溶血性输血反应相关的全血单位来自一名表型为Co(a+b+)的供者。患者既往无输血史；然而，也存在抗-E和抗-c。