Ellisor S S, Reid M E, Avoy D R, Toy P T, Mecoli J
Transfusion. 1982 Mar-Apr;22(2):166-8. doi: 10.1046/j.1537-2995.1982.22282177131.x.
Anti-Gya was identified in the serum of a 71-year-old untransfused man of German descent. The anti-Gya was reactive in the antiglobulin test phase and was of the IgG1 subclass. The patient's red cells typed as Gy(a-). A survival study using 10 ml of ABO compatible Gy(a+) 51Cr labelled red blood cells indicated normal survival up to six days. The anti-Gya diminished in reaction strength, and three months after the patient's initial hospitalization the antibody was no longer demonstrable by standard manual techniques. We conclude that intravascular hemolysis would have been unlikely if this patient were transfused with Gy(a+) cells. However, due to the possibility of a delayed hemolytic transfusion reaction, Gy(a+) cells would have been given only if Gy(a-) cells were not available and the patient's red blood cell deficit were life-threatening.
在一名71岁未输血的德裔男性血清中鉴定出抗-Gya。该抗-Gya在抗球蛋白试验阶段呈反应性，属于IgG1亚类。患者红细胞血型为Gy(a-)。一项使用10毫升ABO相容的Gy(a+) 51Cr标记红细胞的存活研究表明，红细胞存活至6天均正常。抗-Gya反应强度减弱，患者首次住院三个月后，用标准手工技术已无法检测到该抗体。我们得出结论，如果给该患者输注Gy(a+)细胞，发生血管内溶血的可能性不大。然而，由于存在延迟性溶血性输血反应的可能性，只有在没有Gy(a-)细胞且患者红细胞缺乏危及生命的情况下才会输注Gy(a+)细胞。
