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[蒙古人民共和国病毒性肝炎患者、孕妇及新生儿的乙肝抗原(表面抗原和e抗原)及其抗体]

[Hepatitis B antigens (surface and e) and their antibodies in viral hepatitis patients, pregnant women and newborn infants in the Mongolian People's Republic].

作者信息

Vorozhbieva T E, Purévdavaa E, Farber N A, Shakhgil'dian I V, Olzvoĭ G

出版信息

Vopr Virusol. 1982 Jan-Feb(1):53-7.

PMID:7072229
Abstract

The presence of HBs antigen and antibody to it was studied in 516 patients with acute viral hepatitis, convalescents, and patients with chronic liver diseases, 613 pregnant women, and 265 newborn babies using the gel precipitation test, and some of them (747 persons) by the reverse passive hemagglutination (RPHA) test. A high rate of HBs findings was observed both in patients with acute viral hepatitis (54.2%, RPHA) and in convalescents and patients with chronic liver diseases (44.9%, RPHA). Despite wide occurrence of hepatitis B virus carrier state among pregnant women (10.1%, RPHA), the rate of infection in newborn babies was only 0.6% by RPHA. The data are also presented on the distribution of the main subtypes of HBs and HBe antigens and antibody to them in the observed of patients and carriers.

摘要

采用凝胶沉淀试验对516例急性病毒性肝炎患者、恢复期患者及慢性肝病患者、613例孕妇和265例新生儿进行了乙肝表面抗原及其抗体的检测,其中部分患者(747人)采用反向被动血凝试验(RPHA)检测。急性病毒性肝炎患者(RPHA检测阳性率为54.2%)以及恢复期患者和慢性肝病患者(RPHA检测阳性率为44.9%)中乙肝表面抗原的检出率均较高。尽管孕妇中乙肝病毒携带者状态广泛存在(RPHA检测阳性率为10.1%),但新生儿的感染率通过RPHA检测仅为0.6%。还给出了观察对象和携带者中乙肝表面抗原和e抗原及其抗体主要亚型的分布数据。

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