Engelhardt I, Rouvel J, Precht K
Z Urol Nephrol. 1982 Feb;75(2):73-9.
Clinically contradictory results in the use of hollow-fibre dialysers with surfaces of 1.3 and 1.8 m2 prompted us to compare their efficiency under standard conditions. It was found that the efficiency does not increase proportionally to the enlargement of the dialyser surface. the reason for this is to be seen in: the supply of rinsing solution in the dialyser, blood flow, insufficient degassing, coating of the membrane with denatured protein and, last but not least, the body mass of the patient himself. For optimum dialysis an individually suited dialysis time can be calculated from these data for each patient.
临床上，使用表面积为1.3平方米和1.8平方米的中空纤维透析器时出现了相互矛盾的结果，这促使我们在标准条件下比较它们的效率。结果发现，透析器表面积增大时，效率并非成比例提高。其原因在于：透析器中冲洗液的供应、血流量、脱气不足、膜被变性蛋白质覆盖，以及最后但同样重要的，患者自身的体重。为实现最佳透析效果，可根据这些数据为每位患者计算出适合其个体的透析时间。
