• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Changes of plasma amino acids in cirrhotics treated with ornithine salts].

作者信息

Molimard R, Charpentier C, Lemonnier F

出版信息

Ann Nutr Metab. 1982;26(1):25-36. doi: 10.1159/000176540.

DOI:10.1159/000176540
PMID:7073242
Abstract

The plasma amino acid pattern of cirrhotic patients was determined before and after 24 h of continuous infusions of glucose, ornithine alpha-ketoglutarate (O alpha KG), ornithine chlorhydrate (ORN HCl) and sodium ketoglutarate (alpha CGNa). Before treatment, leucine, isoleucine, valine and glutamine levels were low. Tyrosine and methionine levels were high. (See formula in text) was low. Glucose infusions had no effect. O alpha KG increased levels of leucine, isoleucine, valine, alanine and arginine. Threonine, serine, glycine, aspartic acid, methionine, hemicystine, tyrosine and phenylalanine were significantly lowered. (See formula in text) increased. ORN HCl and alpha CGNa did not induce similar changes.

摘要

相似文献

1
[Changes of plasma amino acids in cirrhotics treated with ornithine salts].
Ann Nutr Metab. 1982;26(1):25-36. doi: 10.1159/000176540.
2
Ornithine-alpha-ketoglutarate (OKG) supplementation is more effective than its component salts in traumatized rats.在创伤大鼠中,补充鸟氨酸-α-酮戊二酸(OKG)比补充其组成盐更有效。
J Nutr. 1996 Sep;126(9):2141-50. doi: 10.1093/jn/126.9.2141.
3
Enteral administration of ornithine alpha-ketoglutarate or arginine alpha-ketoglutarate: a comparative study of their effects on glutamine pools in burn-injured rats.鸟氨酸α-酮戊二酸或精氨酸α-酮戊二酸的肠内给药:它们对烧伤大鼠谷氨酰胺池影响的比较研究。
Crit Care Med. 1997 Feb;25(2):293-8. doi: 10.1097/00003246-199702000-00017.
4
[Action of ornighine alpha-ketoglutarate on hyperammoniemia in the cirrhotic patient].[鸟氨酸α-酮戊二酸对肝硬化患者高氨血症的作用]
Presse Med (1893). 1971 Apr 17;79(19):867-8.
5
[Clinical trial of alpha ornithine ketoglutarate].α-鸟氨酸酮戊二酸的临床试验
Lille Med. 1969 Apr;14:Suppl 3:512-5.
6
The use of alpha-ketoglutarate salts in clinical nutrition and metabolic care.α-酮戊二酸盐在临床营养与代谢护理中的应用。
Curr Opin Clin Nutr Metab Care. 1999 Jan;2(1):33-7. doi: 10.1097/00075197-199901000-00007.
7
[Parenteral feeding of patients with liver cirrhosis with hepatic encephalopathy].[对患有肝性脑病的肝硬化患者进行肠外营养]
Infusionsther Klin Ernahr. 1980 Apr;7(2):72-8.
8
Effect of ornithine alpha-ketoglutarate on glutamine pools in burn injury: evidence of component interaction.鸟氨酸α-酮戊二酸对烧伤患者谷氨酰胺储备的影响:成分相互作用的证据
Intensive Care Med. 2007 Mar;33(3):538-41. doi: 10.1007/s00134-006-0511-0. Epub 2007 Jan 18.
9
[Effect of ornithine-ketoglutarate on provoked hyperammonaemia in patients with cirrhosis of the liver (author's transl)].鸟氨酸-α-酮戊二酸对肝硬化患者诱发性高氨血症的影响(作者译)
Cesk Gastroenterol Vyz. 1978 Jun;32(4):262-7.
10
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].[慢性淋巴细胞白血病和急性白血病患者血浆中游离氨基酸的分布]
Wien Klin Wochenschr. 1971 Apr 9;83(14):245-8.

引用本文的文献

1
Ornithine alpha-ketoglutarate: could it be a new therapeutic option for sarcopenia?精氨酸α-酮戊二酸:它会成为肌肉减少症的新治疗选择吗?
J Nutr Health Aging. 2010 Aug;14(7):570-7. doi: 10.1007/s12603-010-0109-7.
2
Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy.L-鸟氨酸-L-天冬氨酸治疗肝性脑病的临床疗效
Metab Brain Dis. 2002 Dec;17(4):453-62. doi: 10.1023/a:1021934607762.
3
Action of ornithine alpha ketoglutarate on DNA synthesis by human fibroblasts.
In Vitro Cell Dev Biol. 1990 Feb;26(2):187-92. doi: 10.1007/BF02624111.