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Prenatal exposure to virilizing progestins: an adult follow-up study of twelve women.

作者信息

Money J, Mathews D

出版信息

Arch Sex Behav. 1982 Feb;11(1):73-83. doi: 10.1007/BF01541367.

DOI:10.1007/BF01541367
PMID:7073470
Abstract

Psychological data were collected on 12 young women, aged 16 to 27 years, with a history of prenatal progestin exposure. In 11 cases, this exposure had induced virilization of the external genitalia. The 12th woman was an anatomically unaffected sister of one of the other women. The sample was composed of 10 women reported on as children by Ehrhardt and Money (1967), Money and Ehrhardt, (1972) as well as two others who were added to this group because they conformed to the original selection criteria for the Money and Ehrhardt studies. Of the 12 women, 10 had completed high school; of these, 7 were in college, 2 were in graduate school, and was raising a family full-time. None of the 12 had a history of difficulty in establishing friendships or dating relationships. Despite childhood characterizations as "tomboys" and avid interest in high school sports, none of the women pursued sports as a career or major pastime. Because of difficulties in personally contacting all 12 women, data on erotic behavior are available for only 6. Only one of these 6, the youngest, reported no erotic experience, and the remaining 5 reported exclusively heterosexual erotic experience and imagery.

摘要

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本文引用的文献

1
Masculinization of female fetus due to use of orally given progestins.
J Am Med Assoc. 1960 Mar 5;172:1028-32. doi: 10.1001/jama.1960.03020100036007.
2
Masculinization of the female fetus associated with administration of oral and intramuscular progestins during gestation: non-adrenal female pseudohermaphrodism.
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Influence of androgen and some aspects of sexually dimorphic behavior in women with the late-treated adrenogenital syndrome.雄激素及某些方面的性二态行为对迟发性肾上腺生殖器综合征女性的影响。
Johns Hopkins Med J. 1968 Sep;123(3):115-22.
4
The effects of testosterone propionate administered before birth on the development of behavior in genetic female rhesus monkeys.出生前给予丙酸睾酮对雌性恒河猴行为发育的影响。
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5
Assessment of estrogen and progestin therapy in gynecology and obstetrics.
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