Gavryck W A, Sattler F R
Arch Neurol. 1982 May;39(5):307-8. doi: 10.1001/archneur.1982.00510170049014.
Streptococcus bovis was isolated from the CSF of a 66-year-old man with meningitis. His clinical appearance was unusual in that he lacked typical signs and symptoms of pyogenic meningitis. Streptococcus bovis was also recovered from his blood, which suggested that bacterial endocarditis was the source of his CNS infection. He was cured after four weeks of therapy with intravenous penicillin G potassium. This is the fourth reported case of meningitis caused by S bovis. The previous three patients also had endocarditis caused by S bovis. Because of the reported propensity of S bovis to infect heart valves and the frequent association of S bovis bacteremia with malignant gastrointestinal (GI) tract tumors, recovery of this organism form CSF should prompt a search for bacterial endocarditis and occult GI cancer.
从一名患有脑膜炎的66岁男性的脑脊液中分离出牛链球菌。他的临床表现不同寻常，因为他缺乏化脓性脑膜炎的典型体征和症状。在他的血液中也发现了牛链球菌，这表明细菌性心内膜炎是他中枢神经系统感染的源头。经过四周静脉注射青霉素G钾治疗后，他痊愈了。这是第四例有报告的由牛链球菌引起的脑膜炎病例。之前的三名患者也患有由牛链球菌引起的心内膜炎。由于有报告称牛链球菌倾向于感染心脏瓣膜，且牛链球菌菌血症常与胃肠道恶性肿瘤相关，因此从脑脊液中分离出这种微生物应促使对细菌性心内膜炎和隐匿性胃肠道癌症进行排查。
