Savage D C
Am J Clin Nutr. 1978 Oct;31(10 Suppl):S131-S135. doi: 10.1093/ajcn/31.10.S131.
Some indigenous microbes form climax communities on gastrointestinal epithelial surfaces during succession in animals of many types. Most communities form in mucous layers on the surfaces, where some microbes in the communities may utilize the mucin as a source of carbon and energy. The mucous gel may also serve physically to stabilize the community. Some microbial types that colonize early during succession may serve, perhaps synergistically with dietary components, to lower the oxygen tension and oxidation-reduction potential so that oxygen-intolerant anaerobes can colonize the epithelial surfaces. Microbes in the communities may adhere to the epithelial surface; the mechanisms by which they adhere may depend upon a variety of factors, including the type of epithelium and the rate of flow of lumenal contents in the areas. Dietary fiber may influence the composition of these communities by providing nutrients for the microbes or altering their environmental conditions including peristaltic rate, mucous concentration and composition, and oxygen tension and oxidation-reduction potential.
在许多类型动物的演替过程中，一些本土微生物会在胃肠道上皮表面形成顶极群落。大多数群落形成于表面的黏液层中，群落中的一些微生物可能利用黏蛋白作为碳源和能量来源。黏液凝胶在物理上也可能有助于稳定群落。一些在演替早期定殖的微生物类型，可能与饮食成分协同作用，降低氧张力和氧化还原电位，从而使不耐氧的厌氧菌能够定殖在上皮表面。群落中的微生物可能会黏附在上皮表面；它们的黏附机制可能取决于多种因素，包括上皮类型和该区域管腔内容物的流动速率。膳食纤维可能通过为微生物提供营养或改变其环境条件（包括蠕动速率、黏液浓度和组成，以及氧张力和氧化还原电位）来影响这些群落的组成。
