Abraham A S, Sonnenblick M, Eini M
Atherosclerosis. 1982 Apr;42(2-3):185-95. doi: 10.1016/0021-9150(82)90149-6.
Eight rabbits, fed on a 1% cholesterol diet for 30 days, were injected daily with potassium chromate for a further 60 days. A 50% reduction in aortic intimal plaque area and in aortic total cholesterol content was observed. However, although levels of serum cholesterol and triglycerides were consistently lower and levels of high density lipoprotein fractions consistently higher in the chromium-treated as compared to the control rabbits, these differences did not reach statistical significance. A further 6 rabbits were injected with potassium chromate and fed on a 1% cholesterol diet for 12 weeks. Mean aortic cholesterol content (+/-SEM) was 40.23 mg/10 cm aortic length (+/-7.50) as compared to 66.24 mg/10 cm (+/- 7.89) in a control group (P less than 0.05), whereas the area of aortic intima covered by macroscopic plaques was 67.5% (+/-2.79) and 81.1% (+/-3.14) (P less than 0.01) respectively.
8只兔子，用1%胆固醇饮食喂养30天，之后每天注射铬酸钾，持续60天。观察到主动脉内膜斑块面积和主动脉总胆固醇含量减少了50%。然而，与对照兔子相比，虽然经铬处理的兔子血清胆固醇和甘油三酯水平持续较低，高密度脂蛋白组分水平持续较高，但这些差异未达到统计学显著性。另外6只兔子注射铬酸钾并采用1%胆固醇饮食喂养12周。平均主动脉胆固醇含量（±标准误）为40.23毫克/10厘米主动脉长度（±7.50），而对照组为66.24毫克/10厘米（±7.89）（P<0.05），而肉眼可见斑块覆盖的主动脉内膜面积分别为67.5%（±2.79）和81.1%（±3.14）（P<0.01）。
