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[噬菌体与细胞受体可逆相互作用模型]

[Model of reversible phage interaction with cell receptors].

作者信息

Ivanitskiĭ G R, Kuniskiĭ A S, Khusainov A A, Tsyganov M A, Deev A A

出版信息

Biofizika. 1982 Mar-Apr;27(2):237-43.

PMID:7074147
Abstract

A model of the bacteriophage behavior at the reversible adsorption stage was investigated. The ratio of concentration of long fibres bound with receptors on bacterial surface to the total concentration of the fibres was taken to be efficiency range of reversible adsorption. To determine this value the expressions for concentrations of all the intermediate forms of the long fibres binding were obtained. The relationship between reversible adsorption efficiency and concentrations of receptors with various values of corresponding constants was computed. The conditions providing different types of cooperativeness in the behavior of the baseplate elements in the process of reversible adsorption were analysed.

摘要

研究了噬菌体在可逆吸附阶段的行为模型。将与细菌表面受体结合的长纤维浓度与纤维总浓度的比值作为可逆吸附的效率范围。为确定该值,得到了长纤维结合所有中间形式浓度的表达式。计算了具有不同相应常数的受体浓度与可逆吸附效率之间的关系。分析了在可逆吸附过程中提供不同类型的基板元件协同行为的条件。

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