头颈部鳞状细胞癌患者的免疫球蛋白同种异型

Immunoglobulin allotypes in patients with squamous cell carcinoma of the head and neck.

作者信息

Ockhuizen T, Pandey J P, Veltri R W, Arlen M, Fudenberg H H

出版信息

Cancer. 1982 May 15;49(10):2021-4. doi: 10.1002/1097-0142(19820515)49:10<2021::aid-cncr2820491013>3.0.co;2-b.

DOI:10.1002/1097-0142(19820515)49:10<2021::aid-cncr2820491013>3.0.co;2-b

Abstract

Gm, A2m, and Km allotypic markers were examined in 40 Caucasian patients with squamous cell carcinomas of the head and neck. Serum IgA levels, the A2m(1) allotypic marker, and antibodies against IgA1, A2m(1), and A2m(2) were measured quantitatively. The frequency of Km(1) was found to be significantly increased in patients with head and neck cancer as compared to the control population.

摘要

在40例患有头颈部鳞状细胞癌的高加索患者中检测了Gm、A2m和Km同种异型标记物。定量测定了血清IgA水平、A2m(1)同种异型标记物以及针对IgA1、A2m(1)和A2m(2)的抗体。结果发现，与对照人群相比，头颈部癌患者中Km(1)的频率显著增加。