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夏威夷结直肠癌患者生存的种族和社会经济地位差异

Racial and socioeconomic status differences in survival of colorectal cancer patients in Hawaii.

作者信息

Wegner E L, Kolonel L N, Nomura A M, Lee J

出版信息

Cancer. 1982 May 15;49(10):2208-16. doi: 10.1002/1097-0142(19820515)49:10<2208::aid-cncr2820491038>3.0.co;2-6.

Abstract

The study reported here examines the survival experience up to 84 months of patients from the five major racial groups in Hawaii diagnosed with colorectal cancer during the years between 1960 and 1974 based on data in the Hawaii Tumor Registry. Previous research in Hawaii showed that racial differences in survival existed even after adjusting for sex, age at diagnosis, stage of the disease at diagnosis, and normal life expectancy. In this paper, socioeconomic status differences between racial groups are hypothesized as a possible explanation for these survival differences. The results show that socioeconomic status did account for some survival differences between racial groups beyond what could be explained by the other variables. After adjusting for all the covariates, the only statistically significant racial differences which remained were higher survival rates for the Japanese patients compared with the rates for the Hawaiian and Filipino patients. Socioeconomic status was not found, however, to have a statistically significant effect on survival independent of race or the other variables examined. Reasons for the modest effects of socioeconomic status in this study are discussed.

摘要

本文所报告的研究基于夏威夷肿瘤登记处的数据,调查了1960年至1974年间在夏威夷被诊断患有结肠直肠癌的五个主要种族群体患者长达84个月的生存经历。此前在夏威夷的研究表明,即使在对性别、诊断时的年龄、诊断时的疾病阶段和正常预期寿命进行调整之后,生存方面的种族差异依然存在。在本文中,种族群体之间的社会经济地位差异被假定为这些生存差异的一种可能解释。结果表明,社会经济地位确实解释了种族群体之间的一些生存差异,而这些差异无法用其他变量来解释。在对所有协变量进行调整之后,唯一具有统计学显著性的种族差异是,与夏威夷人和菲律宾患者相比,日本患者的生存率更高。然而,并未发现社会经济地位独立于种族或所研究的其他变量对生存具有统计学显著性影响。本文讨论了社会经济地位在本研究中影响较小的原因。

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