Tongio M M, Kerschen C, Pauli G, Roeslin N, Grange D, Mayer S
Cancer. 1982 Jun 15;49(12):2485-8. doi: 10.1002/1097-0142(19820615)49:12<2485::aid-cncr2820491212>3.0.co;2-c.
A comparative study of HLA, A, and B antigens frequency was undertaken on patients with primary bronchial carcinoma. A prospective study was carried out on 103 patients admitted for the first time to the hospital, and a retrospective study was done on 53 patients who survived at least five years. Forty-seven patients died early while on the prospective study. The results show an increased frequency of B12 antigen both in patients of the prospective study and the retrospective study. This would suggest that the increase is associated with susceptibility to the disease rather than resistance to it. There was no finding in favor of an association between a HLA antigen and survival.
对原发性支气管癌患者进行了HLA、A和B抗原频率的比较研究。对首次入院的103例患者进行了前瞻性研究，对至少存活5年的53例患者进行了回顾性研究。在前瞻性研究中有47例患者早期死亡。结果显示，前瞻性研究和回顾性研究的患者中B12抗原频率均增加。这表明该增加与疾病易感性相关，而非与疾病抵抗力相关。未发现支持HLA抗原与生存之间存在关联的证据。
