Sebetan I M, Oshida S, Akaishi S
Forensic Sci Int. 1982 May-Jun;19(3):281-6. doi: 10.1016/0379-0738(82)90091-3.
The polymorphism of the transferrin (Tf) system was studied in a total of 300 unrelated Japanese individuals from Miyagi prefecture, the northern part of Japan using isoelectric focusing in thin-layer polyacrylamide gel. In our population samples three common phenotypes and nine variants were observed. The calculated allele frequencies were TfC1 = 0.773, TfC2 = 0.212, TfDchi (Chinese) = 0.008, and the combined frequencies for the TfBvar (variants) = 0.007. Family data (n = 44) were in accordance with an autosomal codominant fashion of inheritance. The use of isoelectric focusing procedure among Japanese will raise the probability of excluding a man falsely accused of paternity to 15.8% as compared with 1.5% when the conventional electrophoretic methods are used.
利用薄层聚丙烯酰胺凝胶中的等电聚焦技术，对来自日本北部宫城县的300名无亲缘关系的日本人的转铁蛋白（Tf）系统多态性进行了研究。在我们的人群样本中，观察到三种常见表型和九种变体。计算得到的等位基因频率为TfC1 = 0.773，TfC2 = 0.212，TfDchi（中国人）= 0.008，TfBvar（变体）的合并频率 = 0.007。家系数据（n = 44）符合常染色体共显性遗传方式。与使用传统电泳方法时的1.5%相比，在日本人中使用等电聚焦程序将排除被错误指控为父系的男性的概率提高到15.8%。
