Funk W G, Lasser E C, Lang J H, Intaglietta M, Hamblin A E
Invest Radiol. 1982 Mar-Apr;17(2):189-92. doi: 10.1097/00004424-198203000-00016.
Purified human C1-esterase inhibitor (C1INH) infused into the circulation of rabbits caused an immediate drop in white blood cell (WBC) count and, simultaneously, a marked decrease in WBC adhesion to the endothelium in the microcirculation. Infusion of iodipamide caused a marked "carpeting" of the venous endothelium by WBC, and this condition was reversed by subsequent infusion of C1INH. The relationship of elevated C1INH to the protective effect of prednisolone on iodipamide toxicity in the rabbit is discussed.
将纯化的人C1酯酶抑制剂（C1INH）注入兔的循环系统会导致白细胞（WBC）计数立即下降，同时，微循环中白细胞与内皮细胞的黏附也显著减少。注入碘番酸会导致白细胞在静脉内皮上明显“铺展”，而随后注入C1INH可逆转这种情况。本文讨论了C1INH升高与泼尼松龙对兔碘番酸毒性的保护作用之间的关系。
