Carruthers C, Baumler A, Neilson A
Oncology. 1977;34(2):47-51. doi: 10.1159/000225179.
Hepatocellular carcinomas and cholangiocarcinomas induced in rat liver by the administration of 3'-methyl-p-dimethyl-aminoazobenzene (3'-Me-DAB) were found to contain a carcinoma distinctive antigen by immunofluorescence, immunoelectrophoresis and immunodiffusion. This carcinoma distinctive antigen does not appear to be alpha-fetoprotein (AFP) or the preneoplastic antigen.
通过给予3'-甲基 - 对二甲氨基偶氮苯(3'-Me-DAB)诱导大鼠肝脏产生的肝细胞癌和胆管癌,经免疫荧光、免疫电泳和免疫扩散法检测发现含有一种癌特异性抗原。这种癌特异性抗原似乎不是甲胎蛋白(AFP)或癌前抗原。