Lund O E
Klin Monbl Augenheilkd. 1982 Jan;180(1):3-12. doi: 10.1055/s-2008-1055002.
The author reports on the experience with 75 cases of optical keratoprosthesis performed since 1967. The keratoprosthesis were carried out either by intracorneal anchoring or according to Strampelli as osteo-odonto-keratoprosthesis. Short-term improvement (up to one year) was achieved in 25% of the cases, there was a improvement (up to 14 years) in eight patients. The operation had to repeated in 30%. The keratoprosthesis is anchored under a firmly attached flap of oral mucosa transplanted to the cornea after cataract operation. Common complications are glaucoma, hypotony syndrome, extrusion of the implant, development of a retroprosthetic membrane and retinal detachment. Only in cases of severe damage to the cornea after alkali or acid burns, trauma, or pemphigoid and failure of previous keratoplasties is a keratoprosthesis indicated. The degree of improvement usually depends on the pre-existing damage to the eye. The possibilities of keratoprosthesis are limited and functional improvement is frequently only of short duration. Intensive counseling and patient care are essential pre-requisites.
作者报告了自1967年以来进行的75例光学角膜移植术的经验。角膜移植术采用角膜内固定或按照斯特兰佩利法进行骨-牙-角膜移植术。25%的病例实现了短期改善（长达一年），8例患者有改善（长达14年）。30%的病例需要再次手术。角膜移植片固定在白内障手术后移植到角膜的牢固附着的口腔黏膜瓣下。常见并发症有青光眼、低眼压综合征、植入物挤出、人工晶状体后膜形成和视网膜脱离。仅在碱或酸烧伤、外伤、类天疱疮后角膜严重受损以及先前角膜移植失败的情况下才考虑进行角膜移植术。改善程度通常取决于眼睛先前存在的损伤。角膜移植术的可能性有限，功能改善往往只是短期的。强化咨询和患者护理是必不可少的先决条件。
