Peo Y C, Shy D S, Chevalier P A
J Biomech Eng. 1982 May;104(2):136-42. doi: 10.1115/1.3138327.
An equation of the form K=C/[1 - (V/V max)]n relating the bulk modulus K to the relative volume V/V max of lung region during inflation-deflation maneuvers is proposed. It well represents the observed fact that the bulk modulus becomes infinitely large when the regional volume approaches its maximum capacity V max. The parameter C describes the bulk modulus at low regional volume whereas the parameter n quantifies the rate at which the bulk modulus changes during the inflation-deflation maneuvers. The mathematical expressions for the regional pressure, P, and volume V , are obtained by integrating the equation K=VdP/dV. They fit exceedingly well with the experimental data recorded during inflation-deflation tests of six excised canine lung lobes.
提出了一个将体积模量(K)与肺区域在充气-放气操作期间的相对体积(V/V_{max})相关联的方程，其形式为(K = C/[1 - (V/V_{max})]^n)。它很好地体现了这样一个观察到的事实，即当区域体积接近其最大容量(V_{max})时，体积模量会变得无穷大。参数(C)描述了低区域体积时的体积模量，而参数(n)量化了在充气-放气操作期间体积模量变化的速率。通过对(K = VdP/dV)方程进行积分，得到了区域压力(P)和体积(V)的数学表达式。它们与六个离体犬肺叶的充气-放气测试期间记录的实验数据拟合得非常好。
