Cailleba A, Moinade S, Gaillard G, Boucher D
Nouv Presse Med. 1982 Apr 17;11(18):1375-7.
Pituitary-gonadal function was studied in 50 male diabetic patients under 53 years of age. Forty-three had normal sexual activity and 7 were impotent. Plasma testosterone levels and urinary 17 ketosteroids, androsterone and dehydroepiandosterone levels were measured. LH and FSH levels before and after LHRH, and prolactin levels before and after TRH were also measured in plasma. No significant changes in pituitary-gonadal function were detected, irrespective of the patient's sexual activity. Neither the type and degree of control of diabetes nor the presence of absence of microangiopathy had any influence on the results. Basal LH and FSH levels were slightly higher in older patients. Prolactin levels after TRH were significantly higher in the later stages of the test in patients with microangiopathy.
对50名53岁以下的男性糖尿病患者的垂体 - 性腺功能进行了研究。43人性生活正常,7人阳痿。测定了血浆睾酮水平、尿17 - 酮类固醇、雄酮和脱氢表雄酮水平。还测定了血浆中促黄体生成素(LH)和促卵泡生成素(FSH)在促性腺激素释放激素(LHRH)刺激前后的水平,以及促甲状腺激素释放激素(TRH)刺激前后的催乳素水平。无论患者的性功能状态如何,均未检测到垂体 - 性腺功能有显著变化。糖尿病的控制类型和程度以及微血管病变的有无均对结果无任何影响。老年患者的基础LH和FSH水平略高。在试验后期,有微血管病变的患者经TRH刺激后的催乳素水平显著升高。