Baranowska B, Misiorowski W, Pacho R, Wysocki M, Kobuszewska M, Zgliczyński S
Nuklearmedizin. 1982 Feb;21(1):16-8.
The aim of this study was to evaluate the usefulness of computed tomography in the localisation of adrenal tumors producing aldosterone and cortisol. One case each of Conn's and Cushing's syndrome are described. The diagnosis of Conn's syndrome was established by demonstrating an elevated plasma aldosterone level "at rest" and its decrease after stimulation, the absence of plasma renin activity and a lowered plasma potassium level. The diagnosis of Cushing's syndrome due to adrenal adenoma was established by demonstrating the typical clinical features, an abnormal diurnal rhythm of cortisol and ACTH secretion and an increased urine excretion of 17-OHCS without suppression by large doses of dexamethasone. The localisation and the size of the tumors as determined by computed tomography were confirmed during surgery.
本研究的目的是评估计算机断层扫描在定位产生醛固酮和皮质醇的肾上腺肿瘤方面的实用性。文中描述了各1例Conn综合征和库欣综合征的病例。Conn综合征的诊断依据是：“静息”时血浆醛固酮水平升高，刺激后降低，血浆肾素活性缺乏以及血浆钾水平降低。肾上腺腺瘤所致库欣综合征的诊断依据是：具有典型的临床特征、皮质醇和促肾上腺皮质激素分泌的昼夜节律异常以及尿17-羟皮质类固醇排泄增加且不被大剂量地塞米松抑制。计算机断层扫描所确定的肿瘤定位和大小在手术中得到了证实。
