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[糖尿病患者胰腺酶分泌、肝功能及胃运动功能紊乱的诊断与治疗]

[Diagnosis and treatment of disorders in pancreatic enzyme secretion, liver function and gastric motor activity in diabetes mellitus].

作者信息

Geller L I, Griaznova M V, Petrenko V F

出版信息

Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):7-12.

PMID:7079261
Abstract

Examination of 106 patients with medium severe and severe forms of diabetes mellitus with a history of the disease of more than 3 years revealed a consistent reduction in the liver blood flow rate, in hepatocyte absorption and metabolic functions, pancreatic enzyme secretion, and gastric contractility. The bromsulphthalein, ujoviridin, and pancreozymin tests, as well as synthetic peptide benzoyl-tyrosyl-para-aminobenzoic acid tolerance test, electromanometric measurements of the cardial and pyloric sphincters tones, intracavitary pressure in the stomach and the rate of the test solution evacuation by the stomach are reliable and sensitive indices of the disturbances in the liver, exocrine portion of the pancreas, and gastric contractility in diabetes patients. Pancreozymin showed hepatotrophic properties, and metoclopramid (cerucal, reglan) increased gastric motility reduced in diabetes.

摘要

对106例病程超过3年的中重度糖尿病患者进行检查发现,肝血流速率、肝细胞吸收和代谢功能、胰腺酶分泌及胃收缩力持续降低。酚四溴酞钠、乌索利定和促胰液素试验,以及合成肽苯甲酰 - 酪氨酰 - 对氨基苯甲酸耐量试验、贲门和幽门括约肌张力的电子测压测量、胃腔内压力和胃排空试验溶液的速率,是糖尿病患者肝脏、胰腺外分泌部分和胃收缩力紊乱的可靠且敏感指标。促胰液素具有促肝细胞生长特性,而甲氧氯普胺(胃复安、瑞复啉)可增强糖尿病患者降低的胃动力。

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1
[Diagnosis and treatment of disorders in pancreatic enzyme secretion, liver function and gastric motor activity in diabetes mellitus].[糖尿病患者胰腺酶分泌、肝功能及胃运动功能紊乱的诊断与治疗]
Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):7-12.
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