Kern S, Hess K, Schiller H
Schweiz Arch Neurol Neurochir Psychiatr. 1982;130(1):13-24.
Fourteen patients with unilateral trigeminal neuropathy of unknown origin were examined 5 to 30 years after onset of the illness. In one patient, sensory loss in the area of the mental nerve was probably due to the pressure of the denture. In another three patients there were signs suggestive of multiple sclerosis. In the remaining ten patients there were no manifestation of any additive progressive disease or polyneuropathy. Unilateral trigeminal neuropathy is a benign disorder. The symptoms can persist, regress or even completely disappear. The significant delay in the reflex response of the blink reflex many years after onset of the disease probably signifies a very extensive involvement in the trigeminal nerve. In this disorder there seems to be no relationship to trigeminal neuralgia. In the examined cases viral etiology of the unilateral trigeminal neuropathy could be postulated. This disorder can extent to all three branches of trigeminal or even facial nerve.
14例病因不明的单侧三叉神经病变患者在发病5至30年后接受了检查。1例患者颏神经区域的感觉丧失可能是由于假牙压迫所致。另外3例患者有提示多发性硬化的体征。其余10例患者未出现任何附加的进行性疾病或多发性神经病的表现。单侧三叉神经病变是一种良性疾病。症状可持续、消退甚至完全消失。疾病发作多年后眨眼反射的反射反应明显延迟可能意味着三叉神经受累范围非常广泛。在这种疾病中似乎与三叉神经痛没有关系。在所检查的病例中,可以推测单侧三叉神经病变的病毒病因。这种疾病可扩展至三叉神经的所有三个分支甚至面神经。