澳大利亚蛇类毒液的体外凝血特性。
In vitro coagulant properties of venoms from Australian snakes.
作者信息
Chester A, Crawford G P
出版信息
Toxicon. 1982;20(2):501-4. doi: 10.1016/0041-0101(82)90014-9.
PMID:7080056
Abstract
The procoagulant properties of venous Australian snakes are limited to prothrombin activation. Venoms of Notechis scutatus, Tropidechis carinatus and Pseudechis porphyriacus require phospholipid, calcium and factor V to maximally activate normal prothrombin. Venoms of Pseudonaja textilis and Oxyuranus microlepidotus activate both normal prothrombin and the decarboxy form and do not require co-factors. The actions of the venom of Oxyuranus scutellatus are dependent on concentration.
摘要
澳大利亚毒蛇的促凝血特性仅限于凝血酶原激活。盾鼻蛇属、澳西蛇属和红腹黑蛇属的毒液需要磷脂、钙和因子V才能最大程度地激活正常凝血酶原。棕伊澳蛇和细鳞太攀蛇的毒液既能激活正常凝血酶原，也能激活脱羧形式的凝血酶原，且不需要辅助因子。盾鳞棘背蛇毒液的作用取决于浓度。
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