Suzuki S, Makino T, Shibata H, Kikuchi K, Senoue I, Nomiyama T, Miwa M, Harasawa S, Tani N, Miwa T
Tokai J Exp Clin Med. 1982 Jan;7(1):111-26.
The mucosal change, the depth of injury and the healing process in the canine gastric wall after Nd-YAG laser (YAG) exposure and electrocautery were studied comparatively by magnified observations. The results were as follows: 1. Mucosal changes caused by the YAG laser beam were more localized within the exposure area than those by electric current. 2. The depth of tissue damage to the canine gastric wall by YAG laser exposure was easy to control when compared to that caused by electrocautery. 3. The healing time of the ulcer caused by the YAG laser was shorter than that caused by high frequency current. 4. In the present study on the mucosal changes due to laser exposure and electrocautery using endoscopy, dissecting microscopy and SEM, it was found that these examinations appear to be helpful as experimental procedures to clarify the detailed appearance of the mucosal surface. It was suggested that endoscopic application of the YAG laser to the gastrointestinal tract was safe and effective when compared with other procedures which have been applied endoscopically for diagnosis and treatment.
通过放大观察，对比研究了Nd-YAG激光（YAG）照射和电灼后犬胃壁的黏膜变化、损伤深度及愈合过程。结果如下：1. YAG激光束引起的黏膜变化比电流引起的更局限于照射区域。2. 与电灼相比，YAG激光照射对犬胃壁的组织损伤深度易于控制。3. YAG激光所致溃疡的愈合时间比高频电流所致的短。4. 在本研究中，利用内镜、解剖显微镜和扫描电子显微镜观察激光照射和电灼引起的黏膜变化，发现这些检查作为阐明黏膜表面详细外观的实验方法似乎是有帮助的。提示与内镜下用于诊断和治疗的其他方法相比，YAG激光内镜下应用于胃肠道是安全有效的。
