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[乙醇胺对实验性大鼠心肌功能亢进中皮质酮浓度的影响]

[Effect of ethanolamine on corticosterone concentration in experimental myocardial hyperfunction in the white rat].

作者信息

Giul'baiazian T A, Kamalian R G

出版信息

Vopr Med Khim. 1982 Mar-Apr;28(2):47-9.

PMID:7080478
Abstract

An initial step of experimental myocardium hyperfunction, caused by coarctation of the subphrenic part of abdominal aorta, was accompanied by a distinct increase in content of corticosterone in rat blood and adrenal glands. Administration of ethanolamine at a dose of 10 mg/kg decreased the hormone content under conditions of heart hyperfunction. The data obtained suggest that adrenal gland cortex was activated in response to the myocardium pathology as well as that content of corticosterone in blood and adrenal glands might be regulated by administration of ethanolamine.

摘要

腹主动脉膈下部分缩窄所致实验性心肌功能亢进的初始阶段,伴随着大鼠血液和肾上腺中皮质酮含量的显著增加。以10mg/kg的剂量给予乙醇胺可降低心脏功能亢进情况下的激素含量。所获得的数据表明,肾上腺皮质因心肌病变而被激活,并且血液和肾上腺中皮质酮的含量可能受乙醇胺给药的调节。

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